In this presentation held at the EuroPython 2014 in Berlin, my colleague Felix Wick demonstrates that setting up a new Python project from scratch can be quite complicated. Especially, structuring your files and directories the right way in order to build a Python package. Thereby, questions are addressed like “Where should my modules, documentation and unit tests go?” and “How do I configure setup.py, Sphinx and so on?” with proven answers! Finally, the template tool PyScaffold is demonstrated that I developed at Blue Yonder. PyScaffold extremely simplifies the process of setting up a new Python project and is freely available to anyone.